Article
ndufa7 plays a critical role in cardiac hypertrophy.
Journal of cellular and molecular medicine - 1 Nov 2020
Shi Xingjuan, Zhang Yu, Chen Ru, Gong Yijie, Zhang Mingming, Guan Rui, Rotstein Ori D, Liu Xiangdong, Wen Xiao-Yan
Abstract excerpt
Cardiac hypertrophy is a common pathological change in patients with progressive cardiac function failure, which can be caused by hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM) or arterial hypertension. Despite years of study, there is still limited knowledge about the underlying molecular mechanisms for cardiac hypertrophy. NDUFA7, a subunit of NADH:ubiquinone oxidoreductase (complex I), has...
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