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Article

Clinical Outcome-Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2020

Dai Wei, Chung Dittman Lai-Shun, Chow Larry Ka-Yue, Yu Valen Zhuoyou, Lei Lisa Chan, Leong Merrin Man-Long, Chan Candy King-Chi, Ko Josephine Mun-Yee, Lung Maria Li

Abstract excerpt

PURPOSE: Investigation of biological mechanisms underlying genetic alterations in cancer can assist the understanding of etiology and identify the potential prognostic biomarkers. EXPERIMENTAL DESIGN: We performed an integrative genomic analysis for a total of 731 nasopharyngeal carcinoma cases from five independent nasopharyngeal carcinoma cohorts to identify the genetic events associated with clinical outcomes....

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PMID: 32988965
DOI: 10.1158/1078-0432.CCR-20-2854

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