Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm

31 Aug 2020

Abstract excerpt

Mammalian oocytes are enveloped by the zona pellucida (ZP), an extracellular matrix of glycoproteins. In sperm, stimulation with ZP proteins evokes a rapid Ca2+ influx via the sperm-specific, pH-sensitive Ca2+ channel CatSper. However, the physiological role and molecular mechanisms underlying ZP-dependent activation of CatSper are unknown. Here, we delineate the sequence of ZP-signaling events in mouse sperm. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ovarian function and disorders
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32984353
DOI: 10.3389/fcell.2020.572735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse SpermPMID 32984353Read ↗

Egg Coat Proteins Activate Calcium Entry into Mouse Sperm via CATSPER Channels1Semantic proximity Read ↗

CatSper: The complex main gate of calcium entry in mammalian spermatozoaSemantic proximity Read ↗

Calcium Signaling Through CatSper Channels in Mammalian FertilizationSemantic proximity Read ↗

The Chemosensing Role of CatSper in Mammalian Sperm: An Updated ReviewSemantic proximity Read ↗

Calcium Channels in the Development, Maturation, and Function of SpermatozoaSemantic proximity Read ↗

Conserved Mechanism of Bicarbonate-Induced Sensitization of CatSper Channels in Human and Mouse SpermSemantic proximity Read ↗

The Control of Male Fertility by Spermatozoan Ion ChannelsSemantic proximity Read ↗

Regulation and roles of Ca2+ stores in human spermSemantic proximity Read ↗

CatSper channel, sperm function and male fertility.Semantic proximity Read ↗

The role of Hv1 and CatSper channels in sperm activationSemantic proximity Read ↗

Regulating the acrosome reactionSemantic proximity Read ↗

The clinical significance of calcium-signalling pathways mediating human sperm hyperactivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.