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Article

The clinical significance of calcium-signalling pathways mediating human sperm hyperactivation

12 Feb 2013

Abstract excerpt

STUDY QUESTION: What is the prevalence of defects in the Ca(2+)-signalling pathways mediating hyperactivation (calcium influx and store mobilization) among donors and sub-fertile patients and are they functionally significant, i.e. related to fertilization success at IVF? SUMMARY ANSWER: This study identifies, for the first time, the prevalence of Ca(2+) store defects in sperm from research donors, IVF and ICSI...

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Share to Ovarian function and disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23406974
DOI: 10.1093/humrep/des467

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