A Mendelian randomization study identified obesity as a causal risk factor of uterine endometrial cancer in Japanese

Abstract excerpt

Causal inference is one of the challenges in epidemiologic studies. Gynecologic diseases have been reported to have association with obesity, however the causality remained controversial except for uterine endometrial cancer. We conducted two-sample Mendelian randomization (MR) analysis using the large-scale genome-wide association study (GWAS) results of gynecologic diseases and body mass index (BMI) in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cancer-related molecular mechanisms research
• Share to Cancer Risks and Factors
• Share to Endometrial and Cervical Cancer Treatments