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The role of mitotype variation and positive epistasis in trait differences between Saccharomyces species.

Genetics - 7 Jan 2026

Wang Jun-Ting Johnson, Ng Ping Ling Priscilla, Powers Maceo E, Rha Catherine H, Brem Rachel B

Abstract excerpt

Many traits of interest in biology evolved long ago and are fixed in a particular species, distinguishing it from other sister taxa. Elucidating the mechanisms underlying such divergences across reproductive barriers has been a key challenge for evolutionary biologists. The yeast Saccharomyces cerevisiae is unique among its relatives for its ability to thrive at high temperature. The genetic determinants of the...

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Identifiers

PMID: 41145224
DOI: 10.1093/genetics/iyaf233
PMCID: PMC12774845

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