Article
Mitochondrial Recombination Reveals Mito-Mito Epistasis in Yeast.
Genetics - 1 May 2018
Wolters John F, Charron Guillaume, Gaspary Alec, Landry Christian R, Fiumera Anthony C, Fiumera Heather L
Abstract excerpt
Genetic variation in mitochondrial DNA (mtDNA) provides adaptive potential although the underlying genetic architecture of fitness components within mtDNAs is not known. To dissect functional variation within mtDNAs, we first identified naturally occurring mtDNAs that conferred high or low fitness in Saccharomyces cerevisiae by comparing growth in strains containing identical nuclear genotypes but different...
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