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Cell type specific gene expression profiling reveals a role for complement component C3 in neutrophil responses to tissue damage

24 Sept 2020

Abstract excerpt

Abstract Tissue damage induces rapid recruitment of leukocytes and changes in the transcriptional landscape that influence wound healing. However, the cell-type specific transcriptional changes that influence leukocyte function and tissue repair have not been well characterized. Here, we employed translating ribosome affinity purification (TRAP) and RNA sequencing, TRAP-seq, in larval zebrafish to identify genes...

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Share to Blood Coagulation and Thrombosis Mechanisms
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PMID: 32973200
DOI: 10.1038/s41598-020-72750-9

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