Article
Tumor-derived exosomes influence the cell cycle and cell migration of human esophageal cancer cell lines.
Cancer science - 1 Dec 2020
Matsumoto Yasunori, Kano Masayuki, Murakami Kentaro, Toyozumi Takeshi, Suito Hiroshi, Takahashi Masahiko, Sekino Nobufumi, Shiraishi Tadashi, Kamata Toshiki, Ryuzaki Takahiro, Hirasawa Soichiro, Kinoshita Kazuya, Matsubara Hisahiro
Abstract excerpt
Our laboratory previously reported the usefulness as biomarkers of exosomes in the plasma of esophageal squamous cell carcinoma (ESCC) patients. However, the influence of tumor-derived exosomes on the tumor itself and underlying mechanisms remain unclear. We here report changes in the phenotype and gene expression when cancer cells exist in an environment with tumor-derived exosomes. The exosomes were isolated...
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