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The Role of Cancer Stem Cell-Derived Exosomes in Cancer Progression

4 May 2022

Abstract excerpt

Cancer stem cells (CSCs) represent a small portion of tumor cells with self-renewal ability in tumor tissues and are a key factor in tumor resistance, recurrence, and metastasis. CSCs produce a large number of exosomes through various mechanisms, such as paracrine and autocrine signaling. Studies have shown that CSC-derived exosomes (CSC-Exos) carry a variety of gene mutations and specific epigenetic...

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PMID: 35571530
DOI: 10.1155/2022/9133658

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