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Article

A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus.

Nature communications - 23 Sept 2020

Harding Christopher J, Huwiler Simona G, Somers Hannah, Lambert Carey, Ray Luke J, Till Rob, Taylor Georgina, Moynihan Patrick J, Sockett R Elizabeth, Lovering Andrew L

Abstract excerpt

Lysozymes are among the best-characterized enzymes, acting upon the cell wall substrate peptidoglycan. Here, examining the invasive bacterial periplasmic predator Bdellovibrio bacteriovorus, we report a diversified lysozyme, DslA, which acts, unusually, upon (GlcNAc-) deacetylated peptidoglycan. B. bacteriovorus are known to deacetylate the peptidoglycan of the prey bacterium, generating an important chemical...

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Identifiers

PMID: 32968056
DOI: 10.1038/s41467-020-18139-8
PMCID: PMC7511926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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