Article
Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19.
PloS one - 1 Jan 2020
Tahseen Sabira, Khanzada Faisal Masood, Rizvi Alamdar Hussain, Qadir Mahmood, Ghazal Aisha, Baloch Aurangzaib Quadir, Mustafa Tehmina
Abstract excerpt
BACKGROUND: Pakistan is among top five high burden countries for tuberculosis and drug resistant TB. Among rifampicin sensitive new pulmonary TB (PTB), prevalence of isoniazid resistance is 8.3% (95%CI: 7.0-10.7) and resistance to fluoroquinolone is higher (11·1%, 95%CI: 7·8-14·3) than isoniazid resistance. METHOD: Five year retrospective data (2015-2019) of drug susceptibility testing (DST) for Mycobacterium...
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