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Article

Drug-resistant Mycobacterium tuberculosis among Nepalese patients at a tuberculosis referral center.

PloS one - 1 Jan 2024

Chand Arun Bahadur, Basnet Ajaya, Maharjan Bhagwan, Rai Ganesh, Joshi Yadav Prasad, Bhatt Lok Raj, Sen Bindu, Rai Shiba Kumar

Abstract excerpt

BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB), characterized by isoniazid and rifampicin resistance, is caused by chromosomal mutations that restrict treatment options and complicate tuberculosis management. This study sought to investigate the prevalence of pre-extensively drug-resistant (pre-XDR) and extensively drug-resistant (XDR) tuberculosis, as well as mutation pattern, in Nepalese patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38709710
DOI: 10.1371/journal.pone.0301210
PMCID: PMC11073693

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