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Article

Identification of spliceosome components pivotal to breast cancer survival.

RNA biology - 1 Jun 2021

An Jing, Luo Zhehui, An Weiwei, Cao Difei, Ma Jianli, Liu Zhaoliang

Abstract excerpt

Cancer cells employ alternative splicing (AS) to acquire splicing isoforms favouring their survival. However, the causes of aberrant AS in breast cancer are poorly understood. In this study, the METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) data were analysed with univariate feature selection. Of 122 analysed spliceosome components, U2SURP, PUF60, DDX41, HNRNPAB, EIF4A3, and PPIL3 were...

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Identifiers

PMID: 32965163
DOI: 10.1080/15476286.2020.1822636
PMCID: PMC8081035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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