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Purine and pyrimidine metabolism regulatory gene signature predicts prognosis and immunotherapy efficiency in breast cancer

2023-07-21

Abstract excerpt

BACKGROUND Breast cancer (BC) is a heterogeneous disease with diverse molecular features and outcomes. Purine and pyrimidine (PP) metabolism provide sufficient nucleotides for tumor growth. Thus, the relationship between PP metabolism and BC needs a thorough exploration. METHODS Based on the 115 PP genes and BC multi-omics data, we performed consensus clustering and functional enrichment analyses to explore the bi...

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Literature Corpus work
c1018210-e981-5a6a-8999-853a02caac24
DOI
10.21203/rs.3.rs-3180802/v1
Open publication

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Purine and pyrimidine metabolism regulatory gene signature predicts prognosis and immunotherapy efficiency in breast cancerDOI 10.21203/rs.3.rs-3180802/v1
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