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Article

AHRR methylation in heavy smokers: associations with smoking, lung cancer risk, and lung cancer mortality.

BMC cancer - 22 Sept 2020

Grieshober Laurie, Graw Stefan, Barnett Matt J, Thornquist Mark D, Goodman Gary E, Chen Chu, Koestler Devin C, Marsit Carmen J, Doherty Jennifer A

Abstract excerpt

BACKGROUND: A low level of methylation at cg05575921 in the aryl-hydrocarbon receptor repressor (AHRR) gene is robustly associated with smoking, and some studies have observed associations between cg05575921 methylation and increased lung cancer risk and mortality. To prospectively examine whether decreased methylation at cg05575921 may identify high risk subpopulations for lung cancer screening among heavy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32962699
DOI: 10.1186/s12885-020-07407-x
PMCID: PMC7510160

Genes

AHRR

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