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Article

Epigenomic targets for the treatment of respiratory disease

2 May 2009

Abstract excerpt

BACKGROUND: A number of processes lead to epigenetic and epigenomic modifications. OBJECTIVE: To address the importance of epigenomics in respiratory disease. METHODS: Studies of epigenomics were analysed in relation to chronic respiratory diseases. RESULTS/CONCLUSION: In lung cancer and mesothelioma, a number of genes involved in carcinogenesis have been demonstrated to be hypermethylated, implicating epigenomic...

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PMID: 19409032
DOI: 10.1517/14728220902926119

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