Article
Nested case-control study of telomere length and lung cancer risk among heavy smokers in the β-Carotene and Retinol Efficacy Trial.
British journal of cancer - 1 May 2018
Doherty Jennifer Anne, Grieshober Laurie, Houck John R, Barnett Matt J, De Dieu Tapsoba Jean, Thornquist Mark D, Wang Ching-Yun, Goodman Gary E, Chen Chu
Abstract excerpt
BACKGROUND: Telomeres protect cells from genomic instability. We examined telomere length and lung cancer risk prospectively in heavy smokers. METHODS: In a nested case-control study with 709 cases and 1313 controls, conditional logistic regression was used to evaluate associations between telomere length (global, chromosome 5p, and 13q) and lung cancer risk by histotype, controlling for detailed smoking history....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.