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Article

AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality.

Thorax - 1 Jul 2017

Bojesen Stig E, Timpson Nicholas, Relton Caroline, Davey Smith George, Nordestgaard Børge G

Abstract excerpt

RATIONALE AND OBJECTIVES: Self-reported smoking underestimates disease risk. Smoking affects DNA methylation, in particular the cg05575921 site in the aryl hydrocarbon receptor repressor (AHRR) gene. We tested the hypothesis that AHRR cg05575921 hypomethylation is associated with risk of smoking-related morbidity and mortality. METHODS: From the Copenhagen City Heart Study representing the Danish general...

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Source

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Identifiers

PMID: 28100713
DOI: 10.1136/thoraxjnl-2016-208789
PMCID: PMC5520281

Genes

AHRR

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