Article
Atypical Chronic Myeloid Leukemia: Where Are We Now?
International journal of molecular sciences - 18 Sept 2020
Crisà Elena, Nicolosi Maura, Ferri Valentina, Favini Chiara, Gaidano Gianluca, Patriarca Andrea
Abstract excerpt
Atypical chronic myeloid leukemia, BCR-ABL1 negative (aCML) is a rare myelodysplastic syndrome (MDS)/myeloproliferative neoplasm (MPN) with a high rate of transformation to acute myeloid leukemia, and poor survival. Until now, the diagnosis has been based on morphological grounds only, possibly making the real frequency of the disease underestimated. Only recently, new insights in the molecular biology of MDS/MPN...
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