Article

Characterization of a novel humanized heavy chain antibody targeting endogenous retroviruses with anti-lymphoma activity

2024-01-18

Abstract excerpt

Lymphomas continue to pose therapeutic challenges, with a considerable portion of patients facing refractory disease. This study focuses on Diffuse Large B-cell Lymphoma (DLBCL), the most prevalent lymphoma type. Within the human genome, transposable elements (TEs), particularly Human Endogenous Retroviruses (HERVs), constitute a significant yet understudied portion. Among HERVs, the HERV-K family, specifically HE...

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Literature Corpus work: faef43ab-5992-5515-bd37-01f69be03480
DOI: 10.1101/2024.01.17.576027

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