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Article

Ageing of the male germ line.

Nature reviews. Urology - 1 Apr 2013

Paul Catriona, Robaire Bernard

Abstract excerpt

Several studies have demonstrated a decline in the male reproductive system, sperm quality, and fertility with advancing paternal age, yet many of the biological mechanisms that underlie this process remain poorly understood. It is unclear whether the problem arises from the progenitor spermatogonial stem cells (for example, from an accumulation of DNA damage and mutations), from the somatic niche present in the...

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Identifiers

PMID: 23443014
DOI: 10.1038/nrurol.2013.18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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