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A distinctive epigenetic ageing profile in human granulosa cells

30 Mar 2020

Abstract excerpt

STUDY QUESTION: Does women's age affect the DNA methylation (DNAm) profile differently in mural granulosa cells (MGCs) from other somatic cells? SUMMARY ANSWER: Accumulation of epimutations by age and a higher number of age-related differentially methylated regions (DMR) in MGCs were found compared to leukocytes from the same woman, suggesting that the MGCs have a distinctive epigenetic profile. WHAT IS KNOWN...

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PMID: 32474592
DOI: 10.1093/humrep/deaa071

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