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Article

The role of RHOT1 and RHOT2 genetic variation on Parkinson disease risk and onset.

Neurobiology of aging - 1 Jan 2021

Periñán María Teresa, Gómez-Garre Pilar, Blauwendraat Cornelis, Mir Pablo, Bandres-Ciga Sara

Abstract excerpt

Genetic variation within the mitochondrial pathway contributes to the risk of Parkinson's disease (PD). Recent genetic analyses have investigated the association between the RHOT1 and RHOT2 genes and PD etiology. Furthermore, 4 mutations in the RHOT1 gene (p.R272Q, p.R450C, p.T351A, p.T610A) have been reported to be potentially associated with disease risk. As part of the International Parkinson Disease Genomics...

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Identifiers

PMID: 32948353
DOI: 10.1016/j.neurobiolaging.2020.07.003
PMCID: PMC7736199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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