No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson’s disease

Abstract excerpt

Sir, In their recent work, Fitzgerald et al. (2017) report a novel homozygous TRAP1 loss-of-function mutation in a patient with late-onset Parkinson’s disease. Further, they show an enrichment of two subgroups of rare TRAP1 variants in controls compared to patients with Parkinson’s disease in the Parkinson’s Progression Markers Initiative (PPMI) dataset (Parkinson Progression Marker Initiative, 2011). However,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetics and Neurodevelopmental Disorders
• Share to Parkinson's Disease Mechanisms and Treatments
• Share to RNA regulation and disease