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Article

Analysis of PTRHD1 common and rare variants in European patients with Parkinson's disease.

Neurobiology of aging - 1 Nov 2021

Sosero Yuri L, Bandres-Ciga Sara, Gan-Or Ziv, Krohn Lynne

Abstract excerpt

Three studies in Iranian and African families identified three different variants in the peptidyl-tRNA hydrolase domain containing 1 gene (PTRHD1) in patients affected by parkinsonism with intellectual impairment. In the current study, our objective was to investigate whether PTRHD1 variants are associated with Parkinson's disease (PD) risk and age at onset (AAO). To evaluate the association between PTRHD1 and PD...

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Identifiers

PMID: 34246528
DOI: 10.1016/j.neurobiolaging.2021.06.005
PMCID: PMC9662088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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