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Article

Phagosome-regulated mTOR signalling during sarcoidosis granuloma biogenesis

17 Sept 2020

Abstract excerpt

Introduction Sarcoidosis and tuberculosis are granulomatous pulmonary diseases characterised by heightened immune reactivity to Mycobacterium tuberculosis antigens. We hypothesised that an unsupervised analysis comparing the molecular characteristics of granulomas formed in response to M. tuberculosis antigens in patients with sarcoidosis or latent tuberculosis infection (LTBI) would provide novel insights into...

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Share to Phagocytosis and Immune Regulation
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PMID: 32943400
DOI: 10.1183/13993003.02695-2020

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