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Article

RNA-sequencing Identifies Novel Pathways in Sarcoidosis Monocytes

26 May 2017

Abstract excerpt

Sarcoidosis is a complex systemic granulomatous disorder of unknown etiology. Genome-wide association studies have not been able to explain a causative role for nucleotide variation in its pathogenesis. The goal of the present study was to identify the gene expression profile and the cellular pathways altered in sarcoidosis monocytes via RNA-sequencing. Peripheral blood monocytes play a role in sarcoidosis...

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PMID: 28577019
DOI: 10.1038/s41598-017-02941-4

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