Article
Genetic polymorphism of CYP11B2 gene and stroke in the Han Chinese population and a meta-analysis.
Pharmacogenetics and genomics - 1 Mar 2011
Tu Yuanchao, Cui Guanglin, Xu Yujun, Bao Xunna, Wang Xiaojing, Wang Dao Wen
Abstract excerpt
OBJECTIVE: The renin-angiotensin-aldosterone system is important for cerebrovascular research because it influences blood pressure, vasoconstriction, thrombosis, and vessel wall damage. We hypothesized that genetic variations in CYP11B2 gene might contribute to the susceptibility for stroke. METHODS AND RESULTS: Here, we present genetic association analyses on CYP11B2 gene variants in two independent ischemic...
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