Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TET2 directs mammary luminal cell differentiation and endocrine response

15 Sept 2020

Abstract excerpt

Epigenetic regulation plays an important role in governing stem cell fate and tumorigenesis. Lost expression of a key DNA demethylation enzyme TET2 is associated with human cancers and has been linked to stem cell traits in vitro; however, whether and how TET2 regulates mammary stem cell fate and mammary tumorigenesis in vivo remains to be determined. Here, using our recently established mammary specific Tet2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32934200
DOI: 10.1038/s41467-020-18129-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TET2 directs mammary luminal cell differentiation and endocrine responsePMID 32934200Read ↗

TET2: A cornerstone in normal and malignant hematopoiesis.Semantic proximity Read ↗

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cellsSemantic proximity Read ↗

TET2 is essential for survival and hematopoietic stem cell homeostasisSemantic proximity Read ↗

TET2 as an epigenetic master regulator for normal and malignant hematopoiesis.Semantic proximity Read ↗

[TET2 as a gatekeeper for hematologic malignancies].Semantic proximity Read ↗

TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiationSemantic proximity Read ↗

TET1 dioxygenase is required for FOXA2-associated chromatin remodeling in pancreatic beta-cell differentiationSemantic proximity Read ↗

Role of TET dioxygenases in the regulation of both normal and pathological hematopoiesis.Semantic proximity Read ↗

TET genes: new players in DNA demethylation and important determinants for stemness.Semantic proximity Read ↗

The TET2 interactors and their links to hematological malignancies.Semantic proximity Read ↗

TET2 in Normal and Malignant Hematopoiesis.Semantic proximity Read ↗

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.