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Mitochondrial DNA copy number and incident atrial fibrillation

15 Sept 2020

Abstract excerpt

BACKGROUND: Mechanistic studies suggest that mitochondria DNA (mtDNA) dysfunction may be associated with increased risk of atrial fibrillation (AF). The association between mtDNA copy number (mtDNA-CN) and incident AF in the general population, however, remains unknown. METHODS: We conducted prospective analyses of 19,709 participants from the Atherosclerosis Risk in Communities Study (ARIC), the Multi-Ethnic...

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PMID: 32933497
DOI: 10.1186/s12916-020-01715-6

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