Article
Molecular detection of antimalarial resistance in Plasmodium vivax isolates from a tertiary care setting in Puducherry.
Indian journal of medical microbiology - 1 Jan 2000
Stanley Pheba, Rajkumari Nonika, Sivaradjy Monika
Abstract excerpt
PURPOSE: The study was aimed at detecting the mutation patterns in the drug targets in Plasmodium vivax that confer resistance to the common antimalarial agents used in India. METHODS: A total of 27 Plasmodium vivax isolates collected from whole blood samples over a three year period were subjected to PCR amplification followed by sequencing of the genes pvmdr1, pvdhfr, pvdhps and pvk12, which serve as the...
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