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Association Between FokI Polymorphism of Vitamin D Receptor Gene and Lumbar Spine Disc Degeneration: A Systematic Review and Meta-Analysis.

American journal of physical medicine & rehabilitation - 1 May 2021

Castillo-Avila Rosa Giannina, González-Castro Thelma Beatriz, Tovilla-Zárate Carlos Alfonso, Juárez-Rojop Isela Esther, López-Narváez María Lilia, Rodríguez-Pérez José Manuel, Suárez-Méndez Samuel

Abstract excerpt

OBJECTIVE: The aim of the present meta-analysis was to explore the association between FokI polymorphism of the vitamin D receptor gene and lumbar spine disc degeneration. DESIGN: The search was performed in PubMed, Scopus, and Web of Science databases up to January 2020. The authors selected nine studies comprising a total of 1549 cases and 1672 controls. The association analysis included the allelic, dominant,...

Topics

Deoxyribonucleases, Type II Site-Specific
Genetic Predisposition to Disease
Humans
Intervertebral Disc Degeneration
Lumbar Vertebrae
Polymorphism, Genetic
Receptors, Calcitriol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32932361
DOI: 10.1097/PHM.0000000000001588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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