Article
Analysis of FokI polymorphism of vitamin D receptor gene in intervertebral disc degeneration.
Genetic testing and molecular biomarkers - 1 Sept 2014
Vieira Luiz Angelo, De Marchi Patricia Leme, dos Santos Aline Amaro, Christofolini Denise Maria, Barbosa Caio Parente, Fonseca Fernando Luiz Affonso, Bianco Bianca, Rodrigues Luciano Miller R
Abstract excerpt
AIM: We have hypothesized a possible relationship between disc degeneration (DD) and VDR FokI/T2C polymorphism. METHODS: A case-control study was performed comprising 121 Brazilian patients with confirmed DD by nuclear magnetic resonance and a control group consisting of 131 healthy patients without a history of disc cysts of the lumbar spine. Detection of VDR FokI/T2C polymorphism was performed using restriction...
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