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Article

Association Between the FokI and ApaI Polymorphisms in the Vitamin D Receptor Gene and Intervertebral Disc Degeneration: A Systematic Review and Meta-Analysis.

Genetic testing and molecular biomarkers - 1 Jan 2017

Pabalan Noel, Tabangay Lani, Jarjanazi Hamdi, Vieira Luiz Angelo, Dos Santos Aline Amaro, Barbosa Caio Parente, Rodrigues Luciano Miller Reis, Bianco Bianca

Abstract excerpt

BACKGROUND: Evidence supporting an association of intervertebral disc degeneration (DD) with polymorphisms of the vitamin D receptor (VDR) gene has been controversial. We performed a meta-analysis of these studies to determine if there was substantial evidence to support such an association between the VDR polymorphisms and DD. METHODS: PubMed, Embase, and Science Direct databases were searched for studies that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27797588
DOI: 10.1089/gtmb.2016.0054

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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