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Article

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects.

Investigative ophthalmology & visual science - 1 Sept 2020

Simcoe Mark J, Khawaja Anthony P, Mahroo Omar A, Hammond Christopher J, Hysi Pirro G

Abstract excerpt

Purpose: The purpose of this study was to identify genetic variants on chromosome X associated with intraocular pressure (IOP) and determine if they possess any sex-specific effects. Methods: Association analyses were performed across chromosome X using 102,407 participants from the UK Biobank. Replication and validation analyses were conducted in an additional 6599 participants from the EPIC-Norfolk cohort, and...

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Share to Chromosomes, Human, X
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotype

Share to Glaucoma, Open-Angle

Share to Intraocular Pressure

Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 32926103
DOI: 10.1167/iovs.61.11.20
PMCID: PMC7490223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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