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Article

Mechanistic insight of DACH1 receptor in the development of carcinoma insurgence through MD simulation studies.

Journal of biomolecular structure & dynamics - 1 Feb 2022

Hassan Mubashir, Zahid Sara, Shahzadi Saba, Malik Erum, Zaib Sumera, Iqbal Jamshed, Shamim Saba, Malik Arif

Abstract excerpt

Proteins are key player in the prognosis and therapeutics of carcinomas through the interactions of downstream signalling cascades. Current work insight the structural and mutational analysis of DACH1 in association with carcinogenesis. The homology modelling was employed to predict mutant and wild protein models and their reliability and accuracy was verified through multiple online approaches. Furthermore, MD...

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PMID: 32924784
DOI: 10.1080/07391102.2020.1818624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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