Article
The not-so-sweet side of sugar: Influence of the microenvironment on the processes that unleash cancer.
Biochimica et biophysica acta. Molecular basis of disease - 1 Dec 2020
Mboge Mam Y, Bissell Mina J
Abstract excerpt
The role of "aerobic glycolysis" in cancer has been examined often in the past. Results from those studies, most of which were performed on two dimensional conditions (2D, tissue culture plastic), demonstrate that aerobic glycolysis occurs as a consequence of oncogenic events. These oncogenic events often drive malignant cell growth and survival. Although 2D based experiments are useful in elucidating the...
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