Article
Glucose metabolism in cancer cells.
Current opinion in clinical nutrition and metabolic care - 1 Jul 2010
Annibaldi Alessandro, Widmann Christian
Abstract excerpt
PURPOSE OF REVIEW: Cancer cells alter their metabolism in order to support their rapid proliferation and expansion across the body. In particular, tumor cells, rather than fueling glucose in the oxidative phosphorylation pathway, generally use glucose for aerobic glycolysis. In this review, we discuss some of the mechanisms thought to be responsible for the acquisition of a glycolytic phenotype in cancer cells...
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