Article
The impact of CYP2D6*4 and GSTP1 Ile105Val polymorphisms on the susceptibility to develop BCR-ABL1 negative myeloproliferative neoplasms.
Molecular biology reports - 1 Oct 2020
Daglar-Aday Aynur, Akadam-Teker Basak, Yonal-Hindilerden Ipek, Dermenci Hasan, Sahin Ezgi, Hindilerden Fehmi, Yilmaz-Aydogan Hulya, Ozturk Oguz, Yavuz Akif Selim
Abstract excerpt
Inter-individual variations in the genes encoding xenobiotic-metabolizing enzymes have been reported to alter susceptibility to various diseases involving hematological disorders. The purpose of this case-control study was to investigate the relationship between CYP2D6*4 and GSTP1 Ile105Val polymorphisms and the risk of developing BCR-ABL1 negative myeloproliferative neoplasms (MPN). PCR-RFLP was used for...
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