Article

Parkinson’s disease-related lncRNA PINK1-AS advances glioma oncogenesis by activating IPO5-RAS signaling pathway

2023-07-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Epidemiological studies have demonstrated a higher incidence of gliomas in patients with Parkinson's disease. However, the underlying molecular mechanisms remain unclear, and insights into why and how patients with Parkinson's disease are susceptible to gliomas are essential for advancing novel therapeutic approaches for both diseases. <bold>Methods:</bold>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3cd4ecef-86f4-52a5-97d8-7b96bba7d4b2
DOI: 10.21203/rs.3.rs-2773876/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Parkinson’s disease-related lncRNA PINK1-AS advances glioma oncogenesis by activating IPO5-RAS signaling pathwayDOI 10.21203/rs.3.rs-2773876/v2Read

The emerging multifaceted role of PINK1 in cancer biologySemantic proximity Read

The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypesSemantic proximity Read

Prognostic and biological roles of Parkinson’s disease genes in cancerSemantic proximity Read

CircRNA PIP5K1A promotes the progression of glioma through upregulation of TCF12/PI3K/AKT pathway by sponging miR-515-5pSemantic proximity Read

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson’s disease patient-iPSCs with LRRK2-G2019S mutationSemantic proximity Read

CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5pSemantic proximity Read

NEAT1 on the Field of Parkinson’s Disease: Offense, Defense, or a Player on the Bench?Semantic proximity Read

Single cell transcriptomics of human PINK1 iPSC differentiation dynamics reveal a core network of Parkinson’s diseaseSemantic proximity Read

PINK1 Overexpression Promotes Cell Migration and Proliferation via Regulation of Autophagy and Predicts a Poor Prognosis in Lung Cancer CasesSemantic proximity Read

LncRNA OIP5-AS1 reduces α-synuclein aggregation and toxicity by targeting miR-126 to activate PLK2 in human neuroblastoma SH-SY5Y cellsSemantic proximity Read

Parkinson’s Disease as a Risk Factor for Prostate Adenocarcinoma: A Molecular Point of ViewSemantic proximity Read

Long-term follow-up of a patient with Parkinson’s disease under nursing care after replacement of fixed implant-supported prostheses with an implant overdenture: a case reportSemantic proximity Read