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Mitophagy in carcinogenesis and cancer treatment

1 Dec 2021

Abstract excerpt

In order to maintain a functional mitochondrial network, cells have developed a quality control mechanism, namely mitophagy. This process can be induced through different pathways. The most studied is the so-called PINK1/Parkin pathway, which is associated with ubiquitylation of several mitochondrial proteins that were initially found to be related to Parkinson's disease. Another type of mitophagy is known as...

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PMID: 35201480
DOI: 10.1007/s12672-021-00454-1

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