Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tau

8 Sept 2020

Abstract excerpt

The repeated failures of amyloid-targeting therapies have challenged our narrow understanding of Alzheimer's disease (AD) pathogenesis and inspired wide-ranging investigations into the underlying mechanisms of disease. Increasing evidence indicates that AD develops from an intricate web of biochemical and cellular processes that extend far beyond amyloid and tau accumulation. This growing recognition surrounding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Biotin and Related Studies
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32898852
DOI: 10.1038/s41386-020-00840-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systems-based proteomics to resolve the biology of Alzheimer’s disease beyond amyloid and tauPMID 32898852Read ↗

Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s diseaseSemantic proximity Read ↗

Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discoverySemantic proximity Read ↗

Proteomic Insight Into Alzheimer's Disease Pathogenesis PathwaysSemantic proximity Read ↗

Proteomics of Alzheimer's disease: Unveiling protein dysregulation in complex neuronal systems.Semantic proximity Read ↗

Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease.Semantic proximity Read ↗

Proteomic analysis of the brain in Alzheimer's disease: molecular phenotype of a complex disease process.Semantic proximity Read ↗

Multiscale proteomic modeling reveals protein networks driving Alzheimer's disease pathogenesis.Semantic proximity Read ↗

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with diseaseSemantic proximity Read ↗

Proteomic landscape of Alzheimer’s disease: emerging technologies, advances and insights (2021 – 2025)Semantic proximity Read ↗

Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?Semantic proximity Read ↗

Network-guided analysis of hippocampal proteome identifies novel proteins that colocalize with Aβ in a mice model of early-stage Alzheimer’s diseaseSemantic proximity Read ↗

Proteomic Atlas of the Human Brain in Alzheimer’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.