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Article

Bazedoxifene inhibits PDGF-BB induced VSMC phenotypic switch via regulating the autophagy level.

Life sciences - 15 Oct 2020

Song Wenmin, Gao Kai, Huang Panhao, Tang Zizhao, Nie Fangqin, Jia Sujie, Guo Ren

Abstract excerpt

There is increasing evidence that Bazedoxifene, as an FDA-approved selective estrogen inhibitor, approved by FDA, not only inhibits estrogen receptors, but also has other pharmacological effects. The purpose of this study was to investigate the effects of Bazedoxifene on the functional changes of vascular smooth muscle cells (VSMCs) after PDGF-BB stimulation. VSMCs were divided into control group, PDGF-BB...

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Identifiers

PMID: 32896557
DOI: 10.1016/j.lfs.2020.118397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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