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Article

Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing.

Parasitology - 1 Mar 2009

von Samson-Himmelstjerna G, Walsh T K, Donnan A A, Carrière S, Jackson F, Skuce P J, Rohn K, Wolstenholme A J

Abstract excerpt

Benzimidazoles (BZ) are widely used to treat parasitic nematode infections of humans and animals, but resistance is widespread in veterinary parasites. Several polymorphisms in beta-tubulin genes have been associated with BZ-resistance. In the present study, we investigated beta-tubulin isotype 1 sequences of 18 Haemonchus contortus isolates with varying levels of resistance to thiabendazole. The only...

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PMID: 19154653
DOI: 10.1017/S003118200800543X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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