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Pyrosequencing analysis of the beta-tubulin gene in Spanish Teladorsagia circumcincta field isolates.

Veterinary parasitology - 23 Mar 2012

Martínez-Valladares María, Donnan Alison, Geldhof Peter, Jackson Frank, Rojo-Vázquez Francisco-Antonio, Skuce Philip

Abstract excerpt

Benzimidazole (BZ) resistance in gastrointestinal nematodes has been associated with single nucleotide polymorphisms (SNPs) at codons 200, 167 and 198 in the beta-tubulin isotype 1 gene and, recently, these SNPs have also been found in macrocyclic lactone (ML) resistant strains of Haemonchus contortus. On this basis, we have studied the same putative SNPs in Spanish Teladorsagia circumcincta field isolates by...

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PMID: 21962969
DOI: 10.1016/j.vetpar.2011.09.009

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Pyrosequencing analysis of the beta-tubulin gene in Spanish Teladorsagia circumcincta field isolates.PMID 21962969Read ↗

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Teladorsagia circumcincta beta tubulin: the presence of the E198L polymorphism on its own is associated with benzimidazole resistance.Semantic proximity Read ↗

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PCR diagnosis of benzimidazole-susceptibility or -resistance in natural populations of the small ruminant parasite, Teladorsagia circumcincta.Semantic proximity Read ↗

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Determination of genomic DNA sequences for beta-tubulin isotype 1 from multiple species of cyathostomin and detection of resistance alleles in third-stage larvae from horses with naturally acquired infectionsSemantic proximity Read ↗

Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcinctaSemantic proximity Read ↗

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Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus.Semantic proximity Read ↗

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