Article
SATB2 in Combination With Cytokeratin 20 Identifies Over 95% of all Colorectal Carcinomas
15 Jun 2011
Abstract excerpt
The special AT-rich sequence-binding protein 2 (SATB2), a nuclear matrix-associated transcription factor and epigenetic regulator, was identified as a tissue type-specific protein when screening protein expression patterns in human normal and cancer tissues using an antibody-based proteomics approach. In this respect, the SATB2 protein shows a selective pattern of expression and, within cells of epithelial...
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