Article
Recent advances in understanding inherited disorders of keratinization
2018-06-27
Abstract excerpt
The ichthyoses are a heterogeneous group of skin diseases characterized by localized or generalized scaling or both. Other common manifestations include palmoplantar keratoderma, erythroderma, recurrent infections, and hypohidrosis. Abnormal barrier function is a cardinal feature of the ichthyoses, which results in compensatory hyperproliferation and transepidermal water loss. Barrier function is maintained primar...
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Identifiers and source
- Literature Corpus work
- 31e7a7c6-340c-5361-9b38-236bbbbb76ae
- DOI
- 10.12688/f1000research.14514.1