Article
Methylphenidate effects on mice odontogenesis and connections with human odontogenesis.
Odontology - 1 Apr 2021
Lima Karol Sartori, Salles Antônio Eduardo Sparça, de Araújo Costa Gabriel, Yokoyama Márjori Frítola, de Paula Ramos Solange, Paixão-Côrtes Vanessa Rodrigues, de Lima Renata Lúcia Leite Ferreira, Salles Maria José Sparça
Abstract excerpt
The purpose of this study is to evaluate the effects of Methylphenidate exposure on mice odontogenesis and connect them by bioinformatics with human odontogenesis. Thirty-two pregnant Swiss mice were divided into treated group and control group, which received, respectively, 5 mg/kg of Methylphenidate and saline solution from the 5th to the 17th day of pregnancy. The mouse embryos tooth germs were analyzed...
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