Article
Zebrafish calls for reinterpretation for the roles of P/Q calcium channels in neuromuscular transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 24 Apr 2013
Wen Hua, Linhoff Michael W, Hubbard Jeffrey M, Nelson Nathan R, Stensland Donald, Dallman Julia, Mandel Gail, Brehm Paul
Abstract excerpt
A long-held tenet of neuromuscular transmission is that calcium-dependent neurotransmitter release is mediated by N-type calcium channels in frog but P/Q-type channels in mammals. The N-type assignment in frog is based principally on pharmacological sensitivity to ω-conotoxin GVIA. Our studies sh...
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